BIO304

Viruses that infect eukaryotic cells have evolved a wide range of strategies to co-opt the biochemical machinery of host cells for the purpose of maximizing virus replication success. Eukaryotic cells have simultaneously evolved mechanisms to limit the extent to which viruses can establish successful infections. This course examines, in large part through the primary literature, the replication biochemistry used by representative examples of mammalian viruses and the cellular biochemical pathways designed to defend cells and organisms from viral takeover. Students are expected to apply what they learn by preparing a grant application narrative as a final project. Prerequisite(s): BIO 242, or BIO 195 and 202, and CHEM 218.